spiral shaped

METPO:1000684 · CLASS · REVIEWED

A cell shape in which an organism has a spiral or helically curved morphology rather than a straight rod or sphere.

Spiral-shape curvature and cell-wall mechanism

Evidence-backed causal sketch linking spiral morphology to scaffold-mediated curvature, peptidoglycan remodeling, and helical/spiral cell geometry.

Spiral-shape curvature and cell-wall mechanism Interactive directed graph showing evidence-backed causal relationships for spiral shaped.

Edge evidence

  • curvature scaffold regulates peptidoglycan remodeling RO:0002211

    Shape scaffolds or complexes bias wall remodeling to create curved and spiral forms.

    • DOI:10.1371/journal.pbio.1002565 cytoplasmic scaffolding proteins ... participate in helical morphogenesis Supports scaffold involvement in helical or spiral morphogenesis.
  • peptidoglycan remodeling enables helical curvature RO:0002327

    Peptidoglycan remodeling enables helical curvature and twist.

    • DOI:10.1016/j.cell.2010.03.046 relaxes peptidoglycan crosslinking, enabling helical cell curvature and twist H. pylori provides a source-backed concrete mechanism for spiral-like helical morphology.
  • helical curvature produces spiral shaped METPO:2000202

    Helical curvature produces a spiral-shaped cell body.

    • DOI:10.1371/journal.pbio.1002565 helical cells Supports helical/spiral cell shape as a recurring bacterial morphology.
  • spiral shaped associated with viscous motility environment biolink:associated_with

    Spiral and curved morphologies can be associated with motility in viscous media.

    • DOI:10.1371/journal.pbio.1002565 helical and curved cells appear to be optimized for motility Functional association is broad and marked as an association, not as a universal cause of the trait.
  • peptidoglycan crosslinking relaxation promotes helical curvature RO:0002213

    Relaxation of peptidoglycan crosslinking promotes helical/spiral shape.

    • DOI:10.3389/fmicb.2023.1162806 Peptidoglycan crosslinking relaxation promotes helical shape and colonization.
  • elongasome entrapment biases biased outer-curve peptidoglycan biosynthesis

    Caging/entrapment of the elongasome biases peptidoglycan insertion toward the outer curve.

    • DOI:10.1038/s41467-024-51790-z Porin-PapS assemblies entrap the cell elongation machinery, biasing peptidoglycan insertion toward the outer curve.
  • biased outer-curve peptidoglycan biosynthesis establishes cell curvature

    A zone of elevated outer-curve peptidoglycan biosynthesis distorts the wall cylinder and establishes curvature.

    • DOI:10.1038/s41467-024-51790-z Creating a longitudinal zone of elevated peptidoglycan biosynthesis distorts the cell-wall cylinder and establishes curvature; ~15% bias suffices.
  • cell curvature produces spiral shaped METPO:2000202

    Sustained cell curvature produces a spiral/helically curved cell.

    • DOI:10.1038/s41467-024-51790-z Curvature established by biased outer-curve growth yields curved/helical cell morphology.
  • periplasmic flagella maintains spiral shaped

    Periplasmic flagella serve as a cytoskeleton that maintains the spiral-shaped cell body.

    • DOI:10.3390/biom14121488 The periplasmic flagella serves as a cytoskeleton to maintain a spiral-shaped cell body.
  • periplasmic flagella distorts cell body

    Periplasmic flagellar filaments distort and push the cell body to shape it.

    • DOI:10.1093/pnasnexus/pgad349 Spirochete flagella inside the periplasm distort and push the cell body.

Provenance

Source
METPO (2025-11-25)
Author
Luke Wang
Definition source
DOI:10.1371/journal.pbio.1002565

Parent traits (1)

Synonyms (3)

  • S_curved_spiral RELATED_SYNONYM · metpo.owl
  • spiral RELATED_SYNONYM · metpo.owl
  • spiral-shaped RELATED_SYNONYM · metpo.owl

kg-microbe context

Matched 1 kg-microbe node via direct_metpo.

  • METPO:1000684 [+2.081, -74.961, -2.345, -78.220, …]

512-dim DeepWalkSkipGramEnsmallen embedding from kg-microbe (2026-04-25).

Nearest neighbors in embedding space

Top-8 cosine-similar METPO traits from the 2026-04-25 deepwalk (512-D).

Curation history

  1. · SEEDED_FROM_METPO · seed_from_metpo

    imported from data/raw/metpo.owl (CLASS)

  2. · CURATED_WITH_LITERATURE · codex

    Added definition and DOI-backed causal graph for spiral morphology, peptidoglycan remodeling, curvature scaffolds, helical curvature, and viscous motility association.

  3. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002327×1, METPO:2000202×1).

  4. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (biolink:associated_with×1).

  5. · RENAME_PREDICATE_LABELS · claude

    Renamed 1 causal-edge predicate label(s) to align with existing groundings: influences → regulates ×1.

  6. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002211×1).

  7. · ENRICH_CAUSAL_GRAPH · claude

    Added 6 evidence-backed generic edges (6 new nodes) from the deep-research report.

  8. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002213×1, METPO:2000202×1).

  9. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0044297×1).