chemoheterotrophic

Edge evidence

• chemoheterotrophic uses energy source organic molecule METPO:2000010

  Chemoheterotrophs derive chemical energy from organic compounds.

  • DOI:10.1021/acsomega.3c02205 organic molecules ... energy source Supports organic molecules as energy sources in chemoheterotrophic growth.
• chemoheterotrophic uses carbon source organic molecule METPO:2000006

  Chemoheterotrophs use organic compounds as carbon sources.

  • DOI:10.1016/B978-012373944-5.00083-3 reduced organic compound Supports organic compounds as carbon sources in chemoheterotrophy.
• organic molecule broken down by catabolism

  Organic molecules are catabolized to release energy and precursors.

  • DOI:10.1016/B978-012373944-5.00083-3 breakdown of nutrients Supports catabolism of organic nutrients.
• catabolism can proceed through respiration

  Organic catabolism can conserve energy through respiration.

  • DOI:10.1016/j.bbabio.2008.09.008 membrane-bound electron transport chain Supports respiratory electron transport as an energy-conserving route.
• catabolism can proceed through fermentation

  Organic catabolism can conserve energy through fermentation.

  • DOI:10.3389/fmicb.2021.703525 substrate ... electron donor as well as acceptor Supports fermentation of organic substrates without external electron acceptors.
• respiration produces ATP METPO:2000202

  Respiration supports ATP synthesis.

  • DOI:10.1016/j.bbabio.2008.09.008 drives ATP synthesis Supports ATP synthesis from respiratory energy conservation.
• fermentation produces ATP METPO:2000202

  Fermentation can produce ATP by substrate-level phosphorylation.

  • DOI:10.1111/1751-7915.13746 substrate-level phosphorylation Supports ATP formation during fermentative metabolism.
• catabolism produces precursor metabolites METPO:2000202

  Catabolism supplies precursors for biosynthesis.

  • DOI:10.1016/B978-012373944-5.00083-3 precursor compounds for anabolism Supports catabolism as a source of biosynthetic precursors.
• precursor metabolites incorporated into biomass biolink:part_of

  Organic-carbon precursors are incorporated into biomass.

  • DOI:10.1016/B978-012373944-5.00083-3 incorporation of a compound into biomass Supports assimilation of compounds into cell material.
• Embden-Meyerhof glycolysis pathway contributes to catabolism RO:0002326

  Embden-Meyerhof glycolysis is a core route of organic-substrate catabolism in chemoheterotrophs.

  • DOI:10.1128/mbio.00992-24 harbor the Embden-Meyerhof-Parnas glycolysis pathway; broad mechanistic core of chemoheterotrophic catabolism.
• fermentation generates short-chain fatty acids biolink:produces

  Fermentation of organic substrates yields short-chain fatty acids such as acetate, succinate, and propionate.

  • DOI:10.1016/j.chom.2024.05.011 subsequent fermentation to short-chain fatty acids (acetate, succinate, propionate); broadly useful fermentation output edge.
• PEP-dependent phosphotransferase system (mannitol PTS) imports and phosphorylates mannitol

  A PEP-dependent phosphotransferase system imports and phosphorylates mannitol as an organic substrate.

  • DOI:10.1016/j.chom.2024.05.011 mannitol is imported/phosphorylated via a PEP-PTS to mannitol-1-phosphate; canonical organotrophic uptake mechanism.
• mtlD mannitol-1-phosphate dehydrogenase converts fructose-6-phosphate

  mtlD converts mannitol-1-phosphate to fructose-6-phosphate, feeding catabolism into glycolysis.

  • DOI:10.1016/j.chom.2024.05.011 converted by mtlD to fructose-6-phosphate and enters glycolysis; bridge from transport to central carbon metabolism.
• fructose-6-phosphate broken down by Embden-Meyerhof glycolysis pathway

  Fructose-6-phosphate is metabolized through the Embden-Meyerhof glycolysis pathway.

  • DOI:10.1016/j.chom.2024.05.011 enters glycolysis; links upstream sugar catabolism to the glycolytic pathway.