UV radiation tolerant

Edge evidence

• ultraviolet radiation challenges UV radiation tolerant METPO:2007406

  UV exposure is the environmental challenge the trait counters.

  • DOI:10.3390/genes14091803 Deinococcus radiodurans tolerates UV-C D10 doses of 700 J/m2.
• nucleotide-excision repair enables UV radiation tolerant RO:0002327

  NER removes UV-induced cyclobutane pyrimidine dimers and 6-4 photoproducts.

  • DOI:10.3390/genes14091803 D. radiodurans tolerates lethal UV-C doses via excision-based repair of UV photoproducts.
• photoreactivation enables UV radiation tolerant RO:0002327

  Photolyase-mediated dimer reversal complements excision repair.

  • DOI:10.1101/cshperspect.a012765 D. radiodurans is the reference organism for extreme UV and ionizing radiation resistance.
• ultraviolet radiation causes cyclobutane pyrimidine dimer biolink:causes

  UV exposure produces cyclobutane pyrimidine dimers, the majority DNA lesion.

  • DOI:10.3390/life14070822 UV produces two primary pyrimidine photoproducts: CPDs (majority lesion) and 6-4PPs; central trait-defining lesion, general across taxa.
• ultraviolet radiation causes pyrimidine (6-4) pyrimidone photoproduct biolink:causes

  UV exposure produces pyrimidine (6-4) pyrimidone photoproducts.

  • DOI:10.3390/life14070822 Principal UV lesions include CPDs and pyrimidine (6-4) pyrimidone photoproducts; strong and general.
• CPD photolyase repairs cyclobutane pyrimidine dimer

  CPD photolyase directly reverses cyclobutane pyrimidine dimers via light-driven electron transfer.

  • DOI:10.3390/ijms241512381 Photolyases directly reverse UV photoproducts; CPD photolyase uses light-driven electron transfer to monomerize CPD dimers; canonical general edge.
• catalase detoxifies reactive oxygen species

  Catalase scavenges UV-induced reactive oxygen species, preventing oxidative damage.

  • DOI:10.3390/microorganisms13040756 Genomic analyses implicate catalases in UV resistance; ROS-scavengers/catalases detoxify ROS and prevent oxidative damage; general antioxidant edge.
• mycosporine-like amino acids absorbs ultraviolet radiation

  MAAs absorb UV-A/UV-B (~309-362 nm) and release it as harmless heat, screening UV.

  • DOI:10.3390/ijms241512381 MAAs absorb ~309-362 nm with high extinction coefficients and release absorbed UV as harmless heat; strong, general for cyanobacteria/algae.
• mycosporine-like amino acids quenches reactive oxygen species

  MAAs act as antioxidants that quench UV-induced reactive oxygen species.

  • DOI:10.3390/ijms241512381 MAAs act as antioxidants/free-radical scavengers and quench ROS induced by PAR, UV-A, and UV-B; strong, mechanism/class-level.