chemolithoheterotrophic

Edge evidence

• chemolithoheterotrophic uses electron donor inorganic chemical donor METPO:2000009

  Chemolithoheterotrophy uses inorganic chemical compounds as electron donors.

  • DOI:10.1016/B978-0-12-378630-2.00219-X oxidize inorganic atoms or molecules Supports inorganic chemical donors in chemolithotrophic metabolism.
• ferrous iron example of inorganic chemical donor rdfs:subClassOf

  Fe(II) is an experimentally supported inorganic donor for chemolithoheterotrophy.

  • DOI:10.1038/s41598-021-81412-3 Fe(II) oxidation provides energy Supports Fe(II) as energy source in engineered chemolithoheterotrophy.
• reduced sulfur compound example of inorganic chemical donor rdfs:subClassOf

  Reduced sulfur compounds can fuel chemolithoheterotrophic metabolism.

  • DOI:10.1128/mBio.01112-19 oxidize sulfur to fuel Supports sulfur oxidation as an energy source coupled to organic compound uptake.
• inorganic chemical donor feeds electrons into respiratory chain METPO:2007402

  Oxidized inorganic donors feed electrons into respiratory energy conservation.

  • DOI:10.1016/j.bbabio.2008.09.008 electron transfer process Supports electron transfer in energy-conserving respiratory chains.
• respiratory chain generates proton motive force biolink:produces

  Respiratory electron transfer generates an ion gradient.

  • DOI:10.1016/j.bbabio.2008.09.008 generation of an electrochemical ion gradient Supports proton motive force generation by membrane electron transport.
• proton motive force drives production of ATP biolink:produces

  Proton motive force powers ATP synthesis.

  • DOI:10.1016/j.bbabio.2008.09.008 drives ATP synthesis Supports ATP production from respiratory energy conservation.
• chemolithoheterotrophic uses carbon source organic compound METPO:2000006

  Organic compounds provide carbon for chemolithoheterotrophic growth.

  • DOI:10.1038/s41598-021-81412-3 glucose as the sole carbon source Supports organic carbon use under inorganic donor oxidizing conditions.
• organic compound imported by organic nutrient uptake

  Organic compounds are taken up for heterotrophic carbon assimilation.

  • DOI:10.1128/mBio.01112-19 uptake of organic compounds Supports organic compound uptake fueled by sulfur oxidation.
• organic nutrient uptake supports formation of biomass

  Uptaken organic carbon supports cell-material production.

  • DOI:10.1016/B978-012373944-5.00083-3 incorporation of a compound into biomass Supports assimilation of organic compounds into biomass.
• Sox sulfur-oxidation pathway enables sulfate RO:0002327

  The conserved soxCDYZAXB gene cluster enables complete oxidation of thiosulfate to sulfate without free intermediates.

  • DOI:10.1038/s41396-021-01163-x Gene clusters of the conserved soxCDYZAXB gene order facilitate the complete oxidation of thiosulfate to sulfate, without free intermediates.
• thiosulfate oxidized by Sox sulfur-oxidation pathway

  Thiosulfate, a reduced inorganic sulfur donor, is oxidized by the Sox pathway.

  • DOI:10.1038/s41396-021-01163-x Sox system mediates complete oxidation of thiosulfate to sulfate.
• branched thiosulfate oxidation pathway produces intermediate elemental sulfur

  Truncated soxXYZAB with reverse Dsr/Apr/Sat oxidizes thiosulfate via an elemental sulfur intermediate.

  • DOI:10.1038/s41396-021-01163-x Branched thiosulfate oxidation pathway in which Dsr operating in reverse oxidizes sulfane-derived sulfur to sulfite, with elemental sulfur as intermediate.
• organic carbon import system supports organic nutrient uptake

  Amino acid and carboxylic acid import systems support organic carbon uptake in heterotrophs and mixotrophs.

  • DOI:10.1038/s41396-021-01163-x Import systems for amino acids and carboxylic acids were overly abundant in mixotrophs and heterotrophs, supporting the organic-carbon dependency of the trait.