chemoorganoheterotrophic

METPO:1000640 · CLASS · REVIEWED

A trophic type in which an organism obtains both energy and carbon from organic compounds through oxidation.

Chemoorganoheterotrophic organic energy and carbon metabolism

DOI-backed graph linking organic molecules as chemical energy, electron, and carbon sources to catabolism, respiration or fermentation, ATP, and biomass.

Chemoorganoheterotrophic organic energy and carbon metabolism Interactive directed graph showing evidence-backed causal relationships for chemoorganoheterotrophic.

Edge evidence

  • chemoorganoheterotrophic uses chemical energy source organic molecule

    Chemoorganoheterotrophs derive energy from organic molecules.

    • DOI:10.1021/acsomega.3c02205 organic molecules ... energy source Supports organic molecules as energy sources in chemoorganoheterotrophy.
  • chemoorganoheterotrophic uses electron donor organic molecule METPO:2000009

    Organic molecules serve as electron sources.

    • DOI:10.1021/acsomega.3c02205 organic molecules ... electron source Supports organic molecules as electron sources in chemoorganoheterotrophy.
  • chemoorganoheterotrophic uses carbon source organic molecule METPO:2000006

    Organic molecules serve as carbon sources.

    • DOI:10.1016/B978-012373944-5.00083-3 reduced organic compound Supports reduced organic compounds as carbon sources for chemoheterotrophy.
  • organic molecule broken down by catabolism

    Catabolism breaks down organic nutrients for energy and precursors.

    • DOI:10.1016/B978-012373944-5.00083-3 breakdown of nutrients Supports catabolism as nutrient breakdown for energy and anabolism.
  • catabolism can proceed through respiration

    Organic catabolism can conserve energy through respiration.

    • DOI:10.1016/j.bbabio.2008.09.008 membrane-bound electron transport chain Supports respiratory electron transport as an energy-conserving catabolic route.
  • catabolism can proceed through fermentation

    Organic catabolism can conserve energy through fermentation.

    • DOI:10.1111/1751-7915.13746 substrate-level phosphorylation Supports fermentation as an ATP-producing route from organic substrate catabolism.
  • respiration produces ATP METPO:2000202

    Respiratory electron transport supports ATP synthesis.

    • DOI:10.1016/j.bbabio.2008.09.008 drives ATP synthesis Supports respiratory ATP synthesis.
  • fermentation produces ATP METPO:2000202

    Fermentation can produce ATP by substrate-level phosphorylation.

    • DOI:10.1111/1751-7915.13746 substrate-level phosphorylation Supports ATP formation during fermentation.
  • catabolism produces precursor metabolites METPO:2000202

    Catabolism yields intermediates that feed biosynthesis.

    • DOI:10.1016/B978-012373944-5.00083-3 precursor compounds for anabolism Supports nutrient breakdown to biosynthetic precursors.
  • precursor metabolites incorporated into biomass biolink:part_of

    Precursor metabolites are incorporated into cell material.

    • DOI:10.1016/B978-012373944-5.00083-3 incorporation of a compound into biomass Supports assimilation of compounds into biomass.
  • substrate transport system enables chemoorganoheterotrophic RO:0002327

    Import of organic substrates by transport systems enables chemoorganoheterotrophic growth.

    • DOI:10.1021/acsomega.3c02205 heterotrophic growth requires import of appropriate organic substrates into the cell
  • organic molecule is required for ATP and NAD(P)H

    Imported organic substrate must be metabolized to synthesize ATP and NAD(P)H.

    • DOI:10.1021/acsomega.3c02205 the entering molecule has to be metabolized in some way for the synthesis of ATP and NAD(P)H
  • organic molecule primarily supplies intracellular energy metabolism

    Organic carbon uptake primarily supplies microbial energy demand.

    • DOI:10.1111/gcb.16925 microorganisms use organic C mainly as an energy source
  • extracellular carbohydrate-active enzymes hydrolyzes complex polysaccharides METPO:2000013

    Extracellular CAZymes hydrolyze complex polysaccharides into monomers for uptake.

    • DOI:10.1186/s40793-024-00572-7 microbes produce extracellular carbohydrate-active enzymes that hydrolyse complex plant polysaccharides
  • substrate transport system feeds into intracellular energy metabolism

    Imported sugars feed into intracellular energy metabolism.

    • DOI:10.1186/s40793-024-00572-7 import monomers and short oligosaccharides for energy and downstream metabolism

Provenance

Source
METPO (2025-11-25)
Definition source
DOI:10.1016/B978-012373944-5.00083-3

Parent traits (1)

Synonyms (1)

  • chemoorganoheterotroph RELATED_SYNONYM · metpo.owl

kg-microbe context

Matched 1 kg-microbe node via direct_metpo.

  • METPO:1000640 [-0.994, -2.623, -3.294, +0.737, …]

512-dim DeepWalkSkipGramEnsmallen embedding from kg-microbe (2026-04-25).

Nearest neighbors in embedding space

Top-8 cosine-similar METPO traits from the 2026-04-25 deepwalk (512-D).

Curation history

  1. · SEEDED_FROM_METPO · seed_from_metpo

    imported from data/raw/metpo.owl (CLASS)

  2. · ADDED_CAUSAL_GRAPH · codex

    Added DOI-backed causal graph for organic molecules as energy, electron, and carbon sources feeding catabolism, respiration or fermentation, ATP, and biomass.

  3. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 5 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000202×3, METPO:2000009×1, METPO:2000006×1).

  4. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (METPO:1007501×1).

  5. · RETYPE_CAUSAL_NODES · claude

    Re-typed 1 causal-node node_type field(s) to align with CausalNodeTypeEnum semantics: biomass: BIOLOGICAL_PROCESS → CHEMICAL ×1.

  6. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (biolink:part_of×1).

  7. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:72695×1).

  8. · ENRICH_CAUSAL_GRAPH · claude

    Added 5 evidence-backed generic edges (5 new nodes) from the deep-research report.

  9. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002327×1).

  10. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000013×1).