organoheterotrophic
METPO:1000664 · CLASS · REVIEWED
A trophic type characterized by the use of organic compounds as both electron donors and primary carbon sources for energy generation and biosynthesis.
Organoheterotrophic organic donor and carbon use
Edge evidence
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organoheterotrophic
uses electron donor
organic compound
METPO:2000009Organoheterotrophy uses organic compounds as electron donors.
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DOI:10.1021/acsomega.3c02205organic molecules ... electron source
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organoheterotrophic
uses carbon source
organic compound
METPO:2000006Heterotrophy uses organic compounds as carbon sources.
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DOI:10.1016/B978-012373944-5.00083-3organic compounds as the primary sources of carbon
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organic compound
metabolized by
central carbon metabolism
Organic compounds enter central metabolism for catabolism and biosynthesis.
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DOI:10.1016/B978-012373944-5.00083-3catabolism
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central carbon metabolism
feeds electrons into
respiratory chain
METPO:2007402Oxidation of organic substrates supplies reducing equivalents to respiratory chains.
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DOI:10.1016/j.bbabio.2008.09.008electron transfer process
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central carbon metabolism
oxidizes carbon to
carbon dioxide
Organic substrate oxidation can release CO2.
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DOI:10.1016/B978-012373944-5.00083-3dissimilation
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respiratory chain
produces
ATP
METPO:2000202Respiratory electron transfer conserves energy as ATP.
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DOI:10.1016/j.bbabio.2008.09.008drives ATP synthesis
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organic compound
assimilated into
biomass
Organic carbon supplies building blocks for biomass.
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DOI:10.1016/B978-012373944-5.00083-3incorporation of a compound into biomass
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glycolysis (Embden-Meyerhof pathway)
enables
central carbon metabolism
RO:0002327A complete glycolytic (Embden-Meyerhof) pathway enables catabolism of organic carbon substrates.
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DOI:10.1128/spectrum.04110-22
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tricarboxylic acid cycle
enables
central carbon metabolism
RO:0002327A complete TCA cycle enables oxidative catabolism of organic substrates within central metabolism.
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DOI:10.1128/spectrum.04110-22
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NADH dehydrogenase (complex I)
contributes to
oxidative phosphorylation
RO:0002326NADH dehydrogenase (complex I) feeds electrons into the respiratory chain for oxidative phosphorylation.
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DOI:10.1128/spectrum.04110-22
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cytochrome bc1 complex (complex III)
contributes to
oxidative phosphorylation
RO:0002326The cytochrome bc1 complex transfers electrons in the respiratory chain supporting oxidative phosphorylation.
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DOI:10.1128/spectrum.04110-22
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oxidative phosphorylation
produces
ATP
METPO:2000202Oxidative phosphorylation conserves respiratory energy as ATP.
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DOI:10.1128/spectrum.04110-22
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Provenance
- Source
- METPO (2025-11-25)
- Author
- Anthea Guo
- Definition source
- DOI:10.1016/B978-012373944-5.00083-3
Parent traits (1)
Synonyms (1)
- organoheterotroph
kg-microbe context
Matched 1 kg-microbe node via direct_metpo.
METPO:1000664[-0.481, -1.211, -3.077, -0.947, …]
Nearest neighbors in embedding space
- physiology trophic type 0.609
- physiology carboxydotrophic 0.607
- physiology photolithoautotrophic 0.605
- physiology hydrogenotrophic 0.604
- physiology lithoheterotrophic 0.596
- physiology lithoautotrophic 0.594
- physiology photoorganoheterotrophic 0.585
- physiology photolithotrophic 0.575
Curation history
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SEEDED_FROM_METPO · seed_from_metpo
imported from data/raw/metpo.owl (CLASS)
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ADDED_CAUSAL_GRAPH · codex
Added DOI-backed causal graph for organic compounds as electron donors and carbon sources supporting respiration, ATP, and biomass.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 3 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000009×1, METPO:2000006×1, METPO:2000202×1).
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GROUND_CAUSAL_PREDICATES · claude
Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2007402×1).
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0022904×1).
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (METPO:1007501×1).
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RETYPE_CAUSAL_NODES · claude
Re-typed 1 causal-node node_type field(s) to align with CausalNodeTypeEnum semantics: biomass: BIOLOGICAL_PROCESS → CHEMICAL ×1.
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:50860×1).
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ENRICH_CAUSAL_GRAPH · claude
Added 5 evidence-backed generic edges (5 new nodes) from the deep-research report.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 5 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002327×2, RO:0002326×2, METPO:2000202×1).
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GROUND_CAUSAL_NODES · claude
Grounded 2 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0006099×1, GO:0006119×1).