organoheterotrophic

METPO:1000664 · CLASS · REVIEWED

A trophic type characterized by the use of organic compounds as both electron donors and primary carbon sources for energy generation and biosynthesis.

Organoheterotrophic organic donor and carbon use

DOI-backed graph linking organic compounds as electron donors and carbon sources to central metabolism, respiratory energy conservation, ATP, and biomass.

Organoheterotrophic organic donor and carbon use Interactive directed graph showing evidence-backed causal relationships for organoheterotrophic.

Edge evidence

  • organoheterotrophic uses electron donor organic compound METPO:2000009

    Organoheterotrophy uses organic compounds as electron donors.

    • DOI:10.1021/acsomega.3c02205 organic molecules ... electron source Supports organic molecules as electron sources in organoheterotrophic categories.
  • organoheterotrophic uses carbon source organic compound METPO:2000006

    Heterotrophy uses organic compounds as carbon sources.

    • DOI:10.1016/B978-012373944-5.00083-3 organic compounds as the primary sources of carbon Supports organic compounds as the carbon source for heterotrophic growth.
  • organic compound metabolized by central carbon metabolism

    Organic compounds enter central metabolism for catabolism and biosynthesis.

    • DOI:10.1016/B978-012373944-5.00083-3 catabolism Supports breakdown of nutrients to provide energy and biosynthetic precursors.
  • central carbon metabolism feeds electrons into respiratory chain METPO:2007402

    Oxidation of organic substrates supplies reducing equivalents to respiratory chains.

    • DOI:10.1016/j.bbabio.2008.09.008 electron transfer process Supports respiratory energy conservation through electron transfer.
  • central carbon metabolism oxidizes carbon to carbon dioxide

    Organic substrate oxidation can release CO2.

    • DOI:10.1016/B978-012373944-5.00083-3 dissimilation Supports oxidation of nutrients to provide energy for biosynthesis and maintenance.
  • respiratory chain produces ATP METPO:2000202

    Respiratory electron transfer conserves energy as ATP.

    • DOI:10.1016/j.bbabio.2008.09.008 drives ATP synthesis Supports ATP synthesis from respiratory energy conservation.
  • organic compound assimilated into biomass

    Organic carbon supplies building blocks for biomass.

    • DOI:10.1016/B978-012373944-5.00083-3 incorporation of a compound into biomass Supports assimilation of organic nutrients into new cell material.
  • glycolysis (Embden-Meyerhof pathway) enables central carbon metabolism RO:0002327

    A complete glycolytic (Embden-Meyerhof) pathway enables catabolism of organic carbon substrates.

    • DOI:10.1128/spectrum.04110-22 Genome annotation identifies a complete glycolysis (Embden-Meyerhof) pathway; standard route for organic carbon catabolism.
  • tricarboxylic acid cycle enables central carbon metabolism RO:0002327

    A complete TCA cycle enables oxidative catabolism of organic substrates within central metabolism.

    • DOI:10.1128/spectrum.04110-22 A complete tricarboxylic acid (TCA) cycle is present, indicating capacity for oxidative catabolism of organic substrates.
  • NADH dehydrogenase (complex I) contributes to oxidative phosphorylation RO:0002326

    NADH dehydrogenase (complex I) feeds electrons into the respiratory chain for oxidative phosphorylation.

    • DOI:10.1128/spectrum.04110-22 A complete oxidative phosphorylation pathway is encoded, including NADH dehydrogenase (nuoABCDEFGHIJKLMN).
  • cytochrome bc1 complex (complex III) contributes to oxidative phosphorylation RO:0002326

    The cytochrome bc1 complex transfers electrons in the respiratory chain supporting oxidative phosphorylation.

    • DOI:10.1128/spectrum.04110-22 A complete oxidative phosphorylation pathway is encoded, including cytochrome bc1 (petABC).
  • oxidative phosphorylation produces ATP METPO:2000202

    Oxidative phosphorylation conserves respiratory energy as ATP.

    • DOI:10.1128/spectrum.04110-22 A complete oxidative phosphorylation pathway is encoded, coupling electron transfer to ATP synthesis.

Provenance

Source
METPO (2025-11-25)
Author
Anthea Guo
Definition source
DOI:10.1016/B978-012373944-5.00083-3

Parent traits (1)

Synonyms (1)

  • organoheterotroph RELATED_SYNONYM · metpo.owl

kg-microbe context

Matched 1 kg-microbe node via direct_metpo.

  • METPO:1000664 [-0.481, -1.211, -3.077, -0.947, …]

512-dim DeepWalkSkipGramEnsmallen embedding from kg-microbe (2026-04-25).

Nearest neighbors in embedding space

Top-8 cosine-similar METPO traits from the 2026-04-25 deepwalk (512-D).

Curation history

  1. · SEEDED_FROM_METPO · seed_from_metpo

    imported from data/raw/metpo.owl (CLASS)

  2. · ADDED_CAUSAL_GRAPH · codex

    Added DOI-backed causal graph for organic compounds as electron donors and carbon sources supporting respiration, ATP, and biomass.

  3. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 3 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000009×1, METPO:2000006×1, METPO:2000202×1).

  4. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2007402×1).

  5. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0022904×1).

  6. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (METPO:1007501×1).

  7. · RETYPE_CAUSAL_NODES · claude

    Re-typed 1 causal-node node_type field(s) to align with CausalNodeTypeEnum semantics: biomass: BIOLOGICAL_PROCESS → CHEMICAL ×1.

  8. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:50860×1).

  9. · ENRICH_CAUSAL_GRAPH · claude

    Added 5 evidence-backed generic edges (5 new nodes) from the deep-research report.

  10. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 5 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002327×2, RO:0002326×2, METPO:2000202×1).

  11. · GROUND_CAUSAL_NODES · claude

    Grounded 2 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0006099×1, GO:0006119×1).