organotrophic

METPO:1000655 · CLASS · REVIEWED

A trophic type in which an organism obtains energy from the oxidation of organic compounds.

Organotrophic organic compound oxidation

DOI-backed graph linking organic electron donors, catabolism, respiratory energy conservation, ATP production, and biomass precursors.

Organotrophic organic compound oxidation Interactive directed graph showing evidence-backed causal relationships for organotrophic.

Edge evidence

  • organotrophic uses electron donor organic compound METPO:2000009

    Organotrophy uses organic compounds as electron donors.

    • DOI:10.1016/B978-012373944-5.00083-3 incorporation of a compound into biomass Supports use and assimilation of organic compounds in microbial growth.
  • glucose example of organic compound rdfs:subClassOf

    Glucose is a representative organic substrate.

    • DOI:10.1021/acsomega.3c02205 glucose metabolism Supports glucose as a microbial organic substrate.
  • organic compound oxidized by catabolism

    Organic substrates are oxidized through catabolic metabolism.

    • DOI:10.1016/B978-012373944-5.00083-3 heterotrophic microorganisms Supports catabolism of organic compounds by heterotrophic microbial metabolism.
  • catabolism feeds electrons into respiratory chain METPO:2007402

    Oxidative catabolism supplies electrons to energy-conserving respiration.

    • DOI:10.1016/j.bbabio.2008.09.008 electron transfer process Supports electron transfer through respiratory chains.
  • respiratory chain generates proton motive force biolink:produces

    Respiratory electron transfer generates an ion gradient.

    • DOI:10.1016/j.bbabio.2008.09.008 generation of an electrochemical ion gradient Supports proton motive force generation by membrane electron transport.
  • proton motive force drives production of ATP biolink:produces

    Proton motive force powers ATP synthesis.

    • DOI:10.1016/j.bbabio.2008.09.008 drives ATP synthesis Supports ATP synthesis from respiratory energy conservation.
  • catabolism produces precursor metabolites METPO:2000202

    Organic-compound catabolism supplies biosynthetic precursors.

    • DOI:10.1016/B978-012373944-5.00083-3 incorporation of a compound into biomass Supports use of compound-derived intermediates for biomass formation.
  • catabolism generates NADH and FADH2 biolink:produces

    Oxidation of organic substrates by catabolic pathways generates reduced electron carriers.

    • DOI:10.1186/s13213-024-01761-y Catabolic pathways (Krebs cycle and beta-oxidation) generate reduced carriers (NADH and FADH2).
  • NADH and FADH2 donates electrons to NADH dehydrogenase (Complex I) METPO:2007403

    NADH donates electrons to NADH dehydrogenase (Complex I) to enter the respiratory chain.

    • DOI:10.1186/s13213-024-01761-y NADH dehydrogenase (Complex I) extracts hydrogen/electrons from NADH; broad canonical ETC-entry edge.
  • NADH dehydrogenase (Complex I) feeds electrons into respiratory chain METPO:2007402

    NADH dehydrogenase passes electrons into the membrane respiratory chain.

    • DOI:10.1186/s13213-024-01761-y Reduced carriers feed electrons into membrane electron-transport systems via NADH dehydrogenase.
  • organic carbon availability increases abundance of organotrophic

    Enriched organic carbon supports proliferation of organotrophs.

    • DOI:10.1038/s41396-023-01437-6 Enriched organic C and dissolved organic C can support the rapid propagation of obligate organotrophic copiotrophs.

Provenance

Source
METPO (2025-11-25)
Definition source
DOI:10.1016/B978-012373944-5.00083-3

Parent traits (1)

Synonyms (2)

  • TT_organotroph RELATED_SYNONYM · metpo.owl
  • organotroph RELATED_SYNONYM · metpo.owl

kg-microbe context

Matched 1 kg-microbe node via direct_metpo.

  • METPO:1000655 [+0.165, -1.239, -2.986, +1.908, …]

512-dim DeepWalkSkipGramEnsmallen embedding from kg-microbe (2026-04-25).

Nearest neighbors in embedding space

Top-8 cosine-similar METPO traits from the 2026-04-25 deepwalk (512-D).

Curation history

  1. · SEEDED_FROM_METPO · seed_from_metpo

    imported from data/raw/metpo.owl (CLASS)

  2. · CURATED_CAUSAL_GRAPH · Codex

    Added DOI-backed organotrophy graph for organic substrate oxidation, respiratory energy conservation, ATP, and biosynthetic precursors.

  3. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000009×1, METPO:2000202×1).

  4. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 2 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (rdfs:subClassOf×1, biolink:produces×1).

  5. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2007402×1).

  6. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (GO:0022904×1).

  7. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (METPO:1007500×1).

  8. · GROUND_CAUSAL_NODES · claude

    Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:50860×1).

  9. · RETYPE_CAUSAL_NODES · claude

    Re-typed 1 causal-node node_type field(s) to align with CausalNodeTypeEnum semantics: proton motive force: BIOLOGICAL_PROCESS → STATE ×1.

  10. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (biolink:produces×1).

  11. · ENRICH_CAUSAL_GRAPH · claude

    Added 4 evidence-backed generic edges (3 new nodes) from the deep-research report.

  12. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 3 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (biolink:produces×1, METPO:2007403×1, METPO:2007402×1).