oxygen preference
METPO:1000601 · CLASS · REVIEWED
A phenotype that is relating to an organism's oxygen requirements or tolerance for growth.
Oxygen-preference O2-availability axis
Edge evidence
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ambient molecular oxygen
defines
oxygen preference
METPO:2007500Ambient molecular-oxygen concentration is the quantitative axis defining oxygen-preference phenotypes.
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DOI:10.3389/fmicb.2014.00674various capacities in their utilization of molecular oxygen
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aerobic
is a
oxygen preference
rdfs:subClassOfAerobic is a child oxygen-preference phenotype.
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DOI:10.3389/fmicb.2014.00674aerobic ... respiration capacities
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anaerobic
is a
oxygen preference
rdfs:subClassOfAnaerobic is a child oxygen-preference phenotype.
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DOI:10.3389/fmicb.2014.00674aerobic, microaerobic, and anaerobic reductases
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microaerophilic
is a
oxygen preference
rdfs:subClassOfMicroaerophilic is a child oxygen-preference phenotype.
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DOI:10.3389/fmicb.2014.00674aerophilic, microaerophilic, or anaerobic
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facultative oxygen preference
is a
oxygen preference
rdfs:subClassOfFacultative oxygen preference is a child oxygen-preference phenotype.
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DOI:10.1111/cmi.13338cope with changing oxygen levels
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O2 as terminal electron acceptor
enables
aerobic
RO:0002327Obligate aerobic growth depends on molecular oxygen as terminal electron acceptor.
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DOI:10.1371/journal.ppat.1012084
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molecular oxygen
serves as
O2 as terminal electron acceptor
Molecular oxygen functions as the terminal electron acceptor in aerobic respiration.
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DOI:10.1371/journal.ppat.1012084
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oxygen / reactive oxygen species stress
upregulates
detoxifying-enzyme gene expression
O2 or H2O2 stress upregulates detoxifying-enzyme genes.
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DOI:10.1128/aem.00606-23
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detoxifying-enzyme gene expression
increases
oxygen tolerance
RO:0002213A larger detoxifying-enzyme repertoire increases survival under oxygen exposure.
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DOI:10.1128/aem.00606-23
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catalase
degrades
hydrogen peroxide
METPO:2000007Catalase rapidly degrades hydrogen peroxide, a reactive oxygen species.
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DOI:10.1038/s43705-023-00251-7
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superoxide dismutase
increases
oxygen tolerance
RO:0002213Higher superoxide dismutase activity is associated with higher oxygen tolerance.
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DOI:10.1038/s43705-023-00251-7
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Provenance
- Source
- METPO (2025-11-25)
- Definition source
- PMID:21413255
Parent traits (1)
Children (10)
- aerobic
METPO:1000602 - aerotolerant
METPO:1000609 - anaerobic
METPO:1000603 - facultative oxygen preference
METPO:1000612 - facultatively aerobic
METPO:1000608 - facultatively anaerobic
METPO:1000605 - microaerophilic
METPO:1000604 - microaerotolerant
METPO:1000610 - obligately aerobic
METPO:1000606 - obligately anaerobic
METPO:1000607
Synonyms (2)
- Physiology and metabolism.oxygen tolerance.oxygen tolerance
- metabolism
kg-microbe context
Matched 1 kg-microbe node via direct_metpo.
METPO:1000601[-1.145, -2.522, -2.827, -0.321, …]
Nearest neighbors in embedding space
- environment microaerotolerant 0.912
- environment aerotolerant 0.766
- environment pressure optimum 0.531
- environment copper tolerant 0.531
- environment desiccation tolerant 0.531
- morphology heterocyst 0.531
- morphology intracellular inclusion 0.531
- morphology magnetosome 0.531
Curation history
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·
SEEDED_FROM_METPO · seed_from_metpo
imported from data/raw/metpo.owl (CLASS)
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CURATED_CAUSAL_GRAPH · claude
Added DOI-backed causal graph framing oxygen preference as the O2-availability axis with child aerobic, anaerobic, microaerophilic, and facultative phenotypes.
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IMPROVED_CAUSAL_GRAPH_EVIDENCE · codex
Replaced PMID fallback CausalEdge references with DOI-backed oxygen-utilization and facultative oxygen-response citations.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 4 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (rdfs:subClassOf×4).
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GROUND_CAUSAL_PREDICATES · claude
Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2007500×1).
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ENRICH_CAUSAL_GRAPH · claude
Added 6 evidence-backed generic edges (8 new nodes) from the deep-research report.
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GROUND_CAUSAL_PREDICATES · claude
Grounded 3 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (RO:0002213×2, RO:0002327×1).
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GROUND_CAUSAL_NODES · claude
Grounded 3 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:15379×1, UniProtKB:A0A071MK53×1, UniProtKB:A0A009QPW9×1).
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GROUND_CAUSAL_NODES · claude
Grounded 1 causal-node grounding field(s) via mappings/node_grounding.tsv (CHEBI:16240×1).
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·
GROUND_CAUSAL_PREDICATES · claude
Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (METPO:2000007×1).