EX DUF
Families
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1,796 of 8,296 families. Page 1 of 36.
| Pfam | Family | Seed status | Characterization | Evidence counts | Proteins | Structures | AlphaFold | Other Mechs | Curation status |
|---|---|---|---|---|---|---|---|---|---|
| PF13193 | AMP-binding enzyme C-terminal domain AMP-binding_C |
EX DUF | UNSCORED | Not scored | 284,163 | 297 | 168,232 | not covered by the cross-Mech scan | SEEDED |
| PF00672 | HAMP domain HAMP |
EX DUF | UNSCORED | Not scored | 257,581 | 46 | 151,473 | not covered by the cross-Mech scan | SEEDED |
| PF00990 | Diguanylate cyclase, GGDEF domain GGDEF |
EX DUF | UNSCORED | Not scored | 238,353 | 70 | 144,091 | not covered by the cross-Mech scan | SEEDED |
| PF01535 | PPR repeat PPR |
EX DUF | UNSCORED | Not scored | 228,033 | 30 | 180,864 | not covered by the cross-Mech scan | SEEDED |
| PF00892 | EamA-like transporter family EamA |
EX DUF | UNSCORED | Not scored | 219,191 | 3 | 143,070 | not covered by the cross-Mech scan | SEEDED |
| PF02687 | FtsX-like permease C-terminal FtsX |
EX DUF | UNSCORED | Not scored | 143,181 | 72 | 90,109 | not covered by the cross-Mech scan | SEEDED |
| PF00563 | EAL domain EAL |
EX DUF | UNSCORED | Not scored | 131,837 | 75 | 78,574 | not covered by the cross-Mech scan | SEEDED |
| PF13715 | CarboxypepD_reg-like domain CarbopepD_reg_2 |
EX DUF | UNSCORED | Not scored | 114,619 | 19 | 74,447 | not covered by the cross-Mech scan | SEEDED |
| PF01554 | MatE MatE |
EX DUF | UNSCORED | Not scored | 99,069 | 43 | 70,770 | not covered by the cross-Mech scan | SEEDED |
| PF01757 | Acyltransferase domain Acyl_transf_3 |
EX DUF | UNSCORED | Not scored | 79,491 | 0 | 51,499 | not covered by the cross-Mech scan | SEEDED |
| PF01925 | Sulfite exporter TauE/SafE TauE |
EX DUF | UNSCORED | Not scored | 74,133 | 0 | 48,156 | not covered by the cross-Mech scan | SEEDED |
| PF01042 | Endoribonuclease L-PSP Ribonuc_L-PSP |
EX DUF | UNSCORED | Not scored | 74,014 | 76 | 48,953 | not covered by the cross-Mech scan | SEEDED |
| PF00924 | Mechanosensitive ion channel, beta-domain MS_channel_2nd |
EX DUF | UNSCORED | Not scored | 69,957 | 65 | 46,372 | not covered by the cross-Mech scan | SEEDED |
| PF01638 | HxlR-like helix-turn-helix HxlR |
EX DUF | UNSCORED | Not scored | 69,591 | 18 | 41,510 | not covered by the cross-Mech scan | SEEDED |
| PF00668 | Condensation domain Condensation |
EX DUF | UNSCORED | Not scored | 68,562 | 107 | 14,105 | not covered by the cross-Mech scan | SEEDED |
| PF03401 | Tripartite tricarboxylate transporter family receptor TctC |
EX DUF | UNSCORED | Not scored | 64,590 | 13 | 38,963 | not covered by the cross-Mech scan | SEEDED |
| PF01168 | Alanine racemase, N-terminal domain Ala_racemase_N |
EX DUF | UNSCORED | Not scored | 61,405 | 114 | 39,913 | not covered by the cross-Mech scan | SEEDED |
| PF11951 | Fungal specific transcription factor domain Fungal_trans_2 |
EX DUF | UNSCORED | Not scored | 61,055 | 4 | 51,044 | not covered by the cross-Mech scan | SEEDED |
| PF01594 | AI-2E family transporter AI-2E_transport |
EX DUF | UNSCORED | Not scored | 58,169 | 2 | 37,191 | not covered by the cross-Mech scan | SEEDED |
| PF01595 | Cyclin M transmembrane N-terminal domain CNNM |
EX DUF | UNSCORED | Not scored | 56,844 | 4 | 38,019 | not covered by the cross-Mech scan | SEEDED |
| PF07717 | Oligonucleotide/oligosaccharide-binding (OB)-fold OB_NTP_bind |
EX DUF | UNSCORED | Not scored | 55,636 | 160 | 34,331 | not covered by the cross-Mech scan | SEEDED |
| PF06429 | Flagellar basal body rod FlgEFG protein C-terminal Flg_bbr_C |
EX DUF | UNSCORED | Not scored | 48,344 | 48 | 31,623 | not covered by the cross-Mech scan | SEEDED |
| PF01207 | Dihydrouridine synthase (Dus) Dus |
EX DUF | UNSCORED | Not scored | 46,157 | 15 | 33,123 | not covered by the cross-Mech scan | SEEDED |
| PF01026 | TatD related DNase TatD_DNase |
EX DUF | UNSCORED | Not scored | 42,146 | 16 | 29,396 | not covered by the cross-Mech scan | SEEDED |
| PF03151 | Triose-phosphate Transporter family TPT |
EX DUF | UNSCORED | Not scored | 41,491 | 2 | 34,453 | not covered by the cross-Mech scan | SEEDED |
| PF02082 | Iron-dependent Transcriptional regulator Rrf2 |
EX DUF | UNSCORED | Not scored | 39,881 | 21 | 25,715 | not covered by the cross-Mech scan | SEEDED |
| PF02585 | GlcNAc-PI de-N-acetylase PIG-L |
EX DUF | UNSCORED | Not scored | 39,336 | 28 | 24,676 | not covered by the cross-Mech scan | SEEDED |
| PF03781 | Sulfatase-modifying factor enzyme 1-like domain FGE-sulfatase |
EX DUF | UNSCORED | Not scored | 38,188 | 65 | 25,146 | not covered by the cross-Mech scan | SEEDED |
| PF04828 | Glutathione-dependent formaldehyde-activating enzyme GFA |
EX DUF | UNSCORED | Not scored | 38,163 | 4 | 26,902 | not covered by the cross-Mech scan | SEEDED |
| PF02754 | Cysteine-rich domain CCG |
EX DUF | UNSCORED | Not scored | 37,412 | 19 | 23,792 | not covered by the cross-Mech scan | SEEDED |
| PF01883 | Iron-sulfur cluster assembly protein FeS_assembly_P |
EX DUF | UNSCORED | Not scored | 37,284 | 15 | 24,936 | not covered by the cross-Mech scan | SEEDED |
| PF02597 | ThiS family ThiS |
EX DUF | UNSCORED | Not scored | 36,990 | 39 | 24,446 | not covered by the cross-Mech scan | SEEDED |
| PF02678 | Pirin Pirin |
EX DUF | UNSCORED | Not scored | 36,769 | 22 | 23,663 | not covered by the cross-Mech scan | SEEDED |
| PF03006 | Haemolysin-III related HlyIII |
EX DUF | UNSCORED | Not scored | 35,375 | 11 | 27,402 | not covered by the cross-Mech scan | SEEDED |
| PF05685 | Putative restriction endonuclease Uma2 |
EX DUF | UNSCORED | Not scored | 35,097 | 4 | 20,569 | not covered by the cross-Mech scan | SEEDED |
| PF01938 | TRAM domain TRAM |
EX DUF | UNSCORED | Not scored | 35,071 | 18 | 24,317 | not covered by the cross-Mech scan | SEEDED |
| PF03357 | Snf7 Snf7 |
EX DUF | UNSCORED | Not scored | 34,943 | 31 | 29,923 | not covered by the cross-Mech scan | SEEDED |
| PF02629 | CoA binding domain CoA_binding |
EX DUF | UNSCORED | Not scored | 34,081 | 92 | 24,075 | not covered by the cross-Mech scan | SEEDED |
| PF01171 | PP-loop domain ATP_bind_3 |
EX DUF | UNSCORED | Not scored | 33,613 | 16 | 23,049 | not covered by the cross-Mech scan | SEEDED |
| PF01661 | Macro domain Macro |
EX DUF | UNSCORED | Not scored | 32,372 | 1,152 | 21,017 | not covered by the cross-Mech scan | SEEDED |
| PF11838 | ERAP1-like C-terminal domain ERAP1_C |
EX DUF | UNSCORED | Not scored | 32,309 | 103 | 24,586 | not covered by the cross-Mech scan | SEEDED |
| PF01255 | Putative undecaprenyl diphosphate synthase Prenyltransf |
EX DUF | UNSCORED | Not scored | 31,979 | 103 | 22,269 | not covered by the cross-Mech scan | SEEDED |
| PF01513 | ATP-NAD kinase N-terminal domain NAD_kinase |
EX DUF | UNSCORED | Not scored | 31,526 | 119 | 23,017 | not covered by the cross-Mech scan | SEEDED |
| PF01641 | SelR domain SelR |
EX DUF | UNSCORED | Not scored | 30,911 | 22 | 21,713 | not covered by the cross-Mech scan | SEEDED |
| PF05977 | Transmembrane secretion effector MFS_3 |
EX DUF | UNSCORED | Not scored | 30,466 | 0 | 17,747 | not covered by the cross-Mech scan | SEEDED |
| PF01458 | SUF system FeS cluster assembly, SufBD core domain SUFBD_core |
EX DUF | UNSCORED | Not scored | 30,443 | 8 | 20,235 | not covered by the cross-Mech scan | SEEDED |
| PF25372 | F-box/LRR-repeat protein 15, leucine rich repeat domain LRR_FBXL15 |
EX DUF | UNSCORED | Not scored | 30,220 | 9 | 24,573 | not covered by the cross-Mech scan | SEEDED |
| PF03478 | KIB1-4 beta-propeller Beta-prop_KIB1-4 |
EX DUF | UNSCORED | Not scored | 29,927 | 0 | 24,983 | not covered by the cross-Mech scan | SEEDED |
| PF00893 | Small Multidrug Resistance protein Multi_Drug_Res |
EX DUF | UNSCORED | Not scored | 28,663 | 20 | 17,571 | not covered by the cross-Mech scan | SEEDED |
| PF01657 | Salt stress response/antifungal Stress-antifung |
EX DUF | UNSCORED | Not scored | 28,393 | 4 | 22,295 | not covered by the cross-Mech scan | SEEDED |
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